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Anti-ING2 Polyclonal Antibody - SAlexa Fluor 532
Cat: K111246P - SAlexa Fluor 532
Summary:
【Product name】:Anti-ING2 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:3622 【Swiss Prot】:Q9H160
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:Recombinant protein of human ING2
【Public Immunogen Range】:1-281aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
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