Anti-PPIE Polyclonal Antibody
Cat: K111248P
Summary:
| 【Product name】：Anti-PPIE Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10450 | 【Swiss Prot】：Q9UNP9 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human PPIE | |
| 【Public Immunogen Range】：1-301aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity; this requires proline isomerase activity.
Verified picture:
Western blot analysis with PPIE antibody diluted at 1:2000;Lane: THP-1,K562,HeLa,Jurkat,HL-60,293T.