Anti-INTS6 Polyclonal Antibody
Cat: K111413P
Summary:
| 【Product name】：Anti-INTS6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：26512 | 【Swiss Prot】：Q9UL03 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:2000-5000.;IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human INTS6 | |
| 【Public Immunogen Range】：10-360aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.
Verified picture:
Western blot analysis with INTS6 antibody diluted at 1:3000;Lane: HepG2.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with INTS6 antibody diluted at 1:50.