Anti-IREB2 Polyclonal Antibody - SAlexa Fluor 660
Cat: K111419P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-IREB2 Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3658 | 【Swiss Prot】：P48200 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human IREB2 | |
| 【Public Immunogen Range】：1-344aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
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