Anti-CASQ2 Polyclonal Antibody - SAlexa Fluor 350
Cat: K111428P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-CASQ2 Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：845 | 【Swiss Prot】：O14958 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CASQ2 | |
| 【Public Immunogen Range】：102-400aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca2+ ions. Regulates the release of lumenal Ca2+ via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
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