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Anti-MAP3K20 Polyclonal Antibody - SAlexa Fluor 532
Cat: K111491P - SAlexa Fluor 532
Summary:
【Product name】:Anti-MAP3K20 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:51776 【Swiss Prot】:Q9NYL2
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:2000-5000;IHC 1:50-200.
【Immunogen】:A synthetic peptide of human MAP3K20
【Public Immunogen Range】:660-710/800aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (PubMed:10924358, PubMed:11836244, PubMed:15342622, PubMed:21224381). Involved in limb development (PubMed:26755636).
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