Anti-TAOK3 Polyclonal Antibody - SAlexa Fluor 350
Cat: K111529P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-TAOK3 Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51347 | 【Swiss Prot】：Q9H2K8 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human TAOK3 | |
| 【Public Immunogen Range】：365-415/898aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).
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