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Anti-SYNE3 Polyclonal Antibody - SAlexa Fluor 405
Cat: K111555P - SAlexa Fluor 405
Summary:
【Product name】:Anti-SYNE3 Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:161176 【Swiss Prot】:Q6ZMZ3
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human SYNE3
【Public Immunogen Range】:730-780/975aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
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