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Anti-ANO1 Polyclonal Antibody
Cat: K111563P
Summary:
【Product name】:Anti-ANO1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:55107 【Swiss Prot】:Q5XXA6
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000;IHC 1:50-200.
【Immunogen】:A synthetic peptide of human ANO1
【Public Immunogen Range】:200-250/986aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Verified picture:
Western blot analysis with ANO1 antibody diluted at 1:2000;Lane: HeLa,HT-29,HEK293,SW480.
Immunohistochemistry of paraffin-embedded Human liver cancer with ANO1 antibody diluted at 1:100.