Anti-CD101 Polyclonal Antibody
Cat: K111566P
Summary:
| 【Product name】：Anti-CD101 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9398 | 【Swiss Prot】：Q93033 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human CD101 | |
| 【Public Immunogen Range】：325-375/1021aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4+ CD56+ leukemic tumor cells.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with CD101 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human thyroid cancer with CD101 antibody diluted at 1:100.