Anti-MPRIP Polyclonal Antibody - HRP
Cat: K111577P - HRP
Summary:
| 【Product name】：Anti-MPRIP Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23164 | 【Swiss Prot】：Q6WCQ1 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human MPRIP | |
| 【Public Immunogen Range】：50-100/1025aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
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