Anti-NEMF Polyclonal Antibody
Cat: K111592P
Summary:
| 【Product name】：Anti-NEMF Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9147 | 【Swiss Prot】：O60524 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human NEMF | |
| 【Public Immunogen Range】：235-285/1076aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex. May indirectly play a role in nuclear export.
Verified picture:
Immunohistochemistry of paraffin-embedded Human stomach cancer with NEMF antibody diluted at 1:200.