Anti-DOCK5 Polyclonal Antibody
Cat: K111691P
Summary:
| 【Product name】：Anti-DOCK5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：80005 | 【Swiss Prot】：Q9H7D0 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000;IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human DOCK5 | |
| 【Public Immunogen Range】：1-351aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).
Verified picture:
Western blot analysis with DOCK5 antibody diluted at 1:2000;Lane: A549.
Immunohistochemistry of paraffin-embedded Human breast cancer with DOCK5 antibody diluted at 1:200.