Anti-CABLES1 Polyclonal Antibody - Biotin
Cat: K111615P - Biotin
Summary:
| 【Product name】：Anti-CABLES1 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：91768 | 【Swiss Prot】：Q8TDN4 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CABLES1 | |
| 【Public Immunogen Range】：1-369aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
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