Anti-Claudin 1 Polyclonal Antibody
Cat: K009994P
Summary:
| 【Product name】：Anti-Claudin 1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9076 | 【Swiss Prot】：O95832 |
| 【Tested applications】：IHC,WB,IF | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:800-2000. IF 1:800-2000. | |
| 【Immunogen】：A synthetic peptide of human Claudin 1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small (20-27 kilodalton (kDa)) proteins with very similar structure. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. Claudin-1 is expressed primarily in keratinocytes and normal mammary epithelial cells.
Verified picture:
Immunohistochemistry of paraffin-embedded human colon cancer with Claudin 1 antibody diluted at 1:1600
Western blot analysis with Claudin 1 antibody diluted at 1:1000;Lane: A431 A549 Mouse fetal liver Mouse fetal kidney Mouse testis Mouse skin Rat skin.
Immunohistochemistry of paraffin-embedded human colon cancer with Claudin 1 antibody diluted at 1:1000.