Anti-VCAM1 Polyclonal Antibody
Cat: K111771P
Summary:
| 【Product name】：Anti-VCAM1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：7412 | 【Swiss Prot】：P19320 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human VCAM1 | |
| 【Public Immunogen Range】：20-370aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Verified picture:
Immunohistochemistry of paraffin-embedded Human esophageal cancer with VCAM1 antibody diluted at 1:100.