Anti-IL23R Polyclonal Antibody
Cat: K111774P
Summary:
| 【Product name】：Anti-IL23R Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：149233 | 【Swiss Prot】：Q5VWK5 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.;IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human IL23R | |
| 【Public Immunogen Range】：1-282aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Verified picture:
Western blot analysis with IL23R antibody diluted at 1:2000;Lane: Human cervical cancer.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with IL23R antibody diluted at 1:200.