Anti-PAK2 Polyclonal Antibody
Cat: K111790P
Summary:
| 【Product name】：Anti-PAK2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5062 | 【Swiss Prot】：Q13177 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. ;IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human PAK2 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Verified picture:
Western blot analysis with PAK2 antibody diluted at 1:2000;Lane: Jurkat,HeLa,PC-3M-IE8,Raji,Jurkat,NIH/3T3,293T,C2C12,RAW264.7,Mouse thymus.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with PAK2 antibody diluted at 1:100.