Anti-ZDHHC20 Polyclonal Antibody
Cat: K111807P
Summary:
| 【Product name】：Anti-ZDHHC20 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：253832 | 【Swiss Prot】：Q5W0Z9 |
| 【Tested applications】：IHC,IF | |
| 【Recommended dilution】：IHC 1:100-300. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human ZDHHC20 | |
| 【Public Immunogen Range】：75-130aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245).
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with ZDHHC20 antibody diluted at 1:200.