Anti-CYP3A4 Polyclonal Antibody - Cy3.5
Cat: K111836P - Cy3.5
Summary:
| 【Product name】：Anti-CYP3A4 Polyclonal Antibody - Cy3.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1576 | 【Swiss Prot】：Q6GRK0 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. ;IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human CYP3A4 | |
| 【Public Immunogen Range】：250-504aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide.
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