Anti-Phospho-PERK (Thr980) Polyclonal Antibody
Cat: K009730P
Summary:
| 【Product name】：Anti-Phospho-PERK (Thr980) Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：13666 | 【Swiss Prot】：Q9Z2B5 |
| 【Tested applications】：FCM,IF,IHC,WB,ELISA | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1ug/Test. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of mouse PERK around the phosphorylation site of Thr980 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010].
Verified picture:
Immunohistochemistry of paraffin-embedded rat kidney with Phospho-PERK (Thr980) antibody diluted at 1:400
Immunohistochemistry of paraffin-embedded rat pancreas with Phospho-PERK (Thr980) antibody diluted at 1:200.