Anti-CD3E(APC) Monoclonal Antibody - SAlexa Fluor 405
Cat: K009967M - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-CD3E(APC) Monoclonal Antibody - SAlexa Fluor 405 | 【Source】：Hamster |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：12501 | 【Swiss Prot】：P22646 |
| 【Tested applications】：FCM | |
| 【Recommended dilution】：FCM 10^6cells加0.1ug | |
| 【Immunogen】：H-2Kb-specific murine cytotoxic T-lymphocyte (CTL) | |
| 【Storage】：Store at 2-8℃. Avoid exposure to light. | |
Background:
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
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