Anti-PROM1 Polyclonal Antibody
Cat: K111894P
Summary:
| 【Product name】：Anti-PROM1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8842 | 【Swiss Prot】：O43490 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.;IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human PROM1 | |
| 【Public Immunogen Range】：5-55/865aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with PROM1 antibody diluted at 1:200.
Western blot analysis with PROM1 antibody diluted at 1:2000;Lane: HT-29.