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Anti-HIST1H3F Polyclonal Antibody
Cat: K111917P
Summary:
【Product name】:Anti-HIST1H3F Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:8968 【Swiss Prot】:P68431
【Tested applications】:WB
【Recommended dilution】:WB 1:8000-12000.
【Immunogen】:Recombinant protein of human HIST1H3F
【Public Immunogen Range】:1-137aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Verified picture:
Western blot analysis with HIST1H3F antibody diluted at 1:10000;Lane: HEK293,A549,293T,COS7,K562,NIH/3T3,Raji,Rat lung,Mouse spleen.