Anti-ATP6V0A2 Polyclonal Antibody - SAlexa Fluor 405
Cat: K111924P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-ATP6V0A2 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23545 | 【Swiss Prot】：Q9Y487 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human ATP6V0A2 | |
| 【Public Immunogen Range】：50-400aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).
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