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Anti-LSM6 Polyclonal Antibody - Biotin
Cat: K111929P - Biotin
Summary:
【Product name】:Anti-LSM6 Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:11157 【Swiss Prot】:P62312
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human LSM6
【Public Immunogen Range】:1-81aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166).The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable).
Verified picture: