Anti-BACE1 Polyclonal Antibody
Cat: K111937P
Summary:
| 【Product name】：Anti-BACE1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23621 | 【Swiss Prot】：P56817 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.;IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human BACE1 | |
| 【Public Immunogen Range】：6-347aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed:10656250, PubMed:10677483, PubMed:20354142).
Verified picture:
Western blot analysis with BACE1 antibody diluted at 1:2000.Lane: Mouse brain.
Immunohistochemistry of paraffin-embedded Human breast cancer with BACE1 antibody diluted at 1:100.