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Anti-BACE1 Polyclonal Antibody - HRP
Cat: K111937P - HRP
Summary:
【Product name】:Anti-BACE1 Polyclonal Antibody - HRP 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:23621 【Swiss Prot】:P56817
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200
【Immunogen】:Recombinant protein of human BACE1
【Public Immunogen Range】:6-347aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed:10656250, PubMed:10677483, PubMed:20354142).
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