Anti-BMPR2 Polyclonal Antibody - SAlexa Fluor 680
Cat: K111943P - SAlexa Fluor 680
Summary:
| 【Product name】：Anti-BMPR2 Polyclonal Antibody - SAlexa Fluor 680 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：659 | 【Swiss Prot】：Q13873 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.;IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human BMPR2 | |
| 【Public Immunogen Range】：600-950aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
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