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Anti-BRD9 Polyclonal Antibody
Cat: K111952P
Summary:
【Product name】:Anti-BRD9 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:65980 【Swiss Prot】:Q9H8M2
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:Recombinant protein of human BRD9
【Public Immunogen Range】:126-473aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797).Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797).Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058).Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR) (PubMed:32457312).
Verified picture:
Western blot analysis with BRD9 antibody diluted at 1:2000.Lane: HeLa,K-562,MCF7,Jurkat,293T.