Anti-HIST1H2AL Polyclonal Antibody
Cat: K111960P
Summary:
| 【Product name】：Anti-HIST1H2AL Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8332 | 【Swiss Prot】：P0C0S8 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human HIST1H2AL | |
| 【Public Immunogen Range】：1-130aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Verified picture:
Immunohistochemistry of paraffin-embedded Human stomach cancer with HIST1H2AL antibody diluted at 1:100.