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Anti-UBXN6 Polyclonal Antibody - SAlexa Fluor 647
Cat: K111989P - SAlexa Fluor 647
Summary:
【Product name】:Anti-UBXN6 Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:80700 【Swiss Prot】:Q9BZV1
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human UBXN6
【Public Immunogen Range】:1-389aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.
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