Anti-UBASH3B Polyclonal Antibody
Cat: K112002P
Summary:
| 【Product name】：Anti-UBASH3B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：84959 | 【Swiss Prot】：Q8TF42 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.; IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human UBASH3B | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
Verified picture:
Western blot analysis with UBASH3B antibody diluted at 1:2000;Lane: HEK293.
Immunohistochemistry of paraffin-embedded Human Thyroid cancer with UBASH3B antibody diluted at 1:200.