Anti-UBASH3B Polyclonal Antibody - RBITC
Cat: K112002P - RBITC
Summary:
| 【Product name】：Anti-UBASH3B Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：84959 | 【Swiss Prot】：Q8TF42 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human UBASH3B | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
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