Anti-DDX6 Polyclonal Antibody
Cat: K112023P
Summary:
| 【Product name】：Anti-DDX6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1656 | 【Swiss Prot】：P26196 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.; IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human DDX6 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts.
Verified picture:
Western blot analysis with DDX6 antibody diluted at 1:2000;Lane: HEK293,K-562,Mouse testis.
Immunohistochemistry of paraffin-embedded Human Testis cancer with DDX6 antibody diluted at 1:200.