Anti-WASF1 Polyclonal Antibody
Cat: K112045P
Summary:
| 【Product name】：Anti-WASF1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：8936 | 【Swiss Prot】：Q92558 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human WASF1 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation.The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity).As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).Also involved in the regulation of mitochondrial dynamics.
Verified picture:
Immunohistochemistry of paraffin-embedded Human Colorectal cancer with WASF1 antibody diluted at 1:100.