Anti-SPC25 Polyclonal Antibody
Cat: K112053P
Summary:
| 【Product name】：Anti-SPC25 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：57405 | 【Swiss Prot】：Q9HBM1 |
| 【Tested applications】：IHC,ELISA,WB | |
| 【Recommended dilution】：WB 1:1000-3000.; IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SPC25 | |
| 【Public Immunogen Range】：1-224aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Verified picture:
Western blot analysis with SPC25 antibody diluted at 1:2000;Lane: K562,Jurkat,U-251,HeLa,PC-3M-IE8.
Immunohistochemistry of paraffin-embedded Human Colorectal cancer with SPC25 antibody diluted at 1:100.