Anti-SERPINE1 Polyclonal Antibody
Cat: K112064P
Summary:
| 【Product name】：Anti-SERPINE1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：5054 | 【Swiss Prot】：P05121 |
| 【Observed】：47kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SERPINE1 | |
| 【Public Immunogen Range】：1-403aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with SERPINE1 antibody diluted at 1:2000;Lane: A549,HepG2,SHSY5Y.
Immunohistochemistry of paraffin-embedded human breast cancer with SERPINE1 antibody diluted at 1:100.