Anti-DKK1 Polyclonal Antibody
Cat: K112069P
Summary:
| 【Product name】：Anti-DKK1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：22943 | 【Swiss Prot】：O94907 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human DKK1 | |
| 【Public Immunogen Range】：1-269aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse brain with DKK1 antibody diluted at 1:200.