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Anti-BMP7 Polyclonal Antibody - SAlexa Fluor 555
Cat: K112085P - SAlexa Fluor 555
Summary:
【Product name】:Anti-BMP7 Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:655 【Swiss Prot】:P18075
【Observed】:49kDa
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human BMP7
【Public Immunogen Range】:51-400aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients.
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