Anti-TULP3 Polyclonal Antibody - SAlexa Fluor 750
Cat: K112139P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-TULP3 Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7289 | 【Swiss Prot】：O75386 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TULP3 | |
| 【Public Immunogen Range】：1-443aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
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