Anti-PRAG1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K112164P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-PRAG1 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：157285 | 【Swiss Prot】：Q86YV5 |
| 【Observed】：100kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of Human PRAG1 | |
| 【Public Immunogen Range】：240-290/1406aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth (By similarity). Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism (By similarity). Acts as a critical coactivator of Notch signaling (By similarity).
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