Anti-MYOM2 Polyclonal Antibody
Cat: K112201P
Summary:
| 【Product name】：Anti-MYOM2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9172 | 【Swiss Prot】：P54296 |
| 【Observed】：190kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of Human MYOM2 | |
| 【Public Immunogen Range】：605-655/1465aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical.
Verified picture:
Western blot analysis with MYOM2 antibody diluted at 1:2000;Lane: Mouse heart,Mouse skeletal muscle,Rat heart,Rat skeletal muscle.
Immunohistochemistry of paraffin-embedded human colorectal cancer with MYOM2 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded human thyroid cancer with MYOM2 antibody diluted at 1:100.