Anti-ARHGEF11 Polyclonal Antibody
Cat: K112209P
Summary:
| 【Product name】：Anti-ARHGEF11 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9826 | 【Swiss Prot】：O15085 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of Human ARHGEF11 | |
| 【Public Immunogen Range】：1250-1300/1522aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Verified picture:
Immunohistochemistry of paraffin-embedded human breast cancer with ARHGEF11 antibody diluted at 1:100.