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Anti-CPB2 Polyclonal Antibody - SAlexa Fluor 750
Cat: K112279P - SAlexa Fluor 750
Summary:
【Product name】:Anti-CPB2 Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1361 【Swiss Prot】:Q96IY4
【Observed】:49kDa
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human CPB2
【Public Immunogen Range】:1-429aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.
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