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Anti-PIH1D1 Polyclonal Antibody
Cat: K112283P
Summary:
【Product name】:Anti-PIH1D1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:55011 【Swiss Prot】:Q9NWS0
【Observed】:38kDa
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:2000-5000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human PIH1D1
【Public Immunogen Range】:1-290aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026).Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451).Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032).Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
Verified picture:
Western blot analysis with PIH1D1 antibody diluted at 1:2000;Lane: HeLa,HMC1,K562.
Immunohistochemistry of paraffin-embedded human breast cancer with PIH1D1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded human endometrial cancer with PIH1D1 antibody diluted at 1:100.