Anti-ANKS1B Polyclonal Antibody
Cat: K112306P
Summary:
| 【Product name】：Anti-ANKS1B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：56899 | 【Swiss Prot】：Q7Z6G8 |
| 【Observed】：80kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human ANKS1B | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.
Verified picture:
Western blot analysis with ANKS1B antibody diluted at 1:2000;Lane: PC-3M-IE8,SHSY5Y.
Immunohistochemistry of paraffin-embedded mouse brain with ANKS1B antibody diluted at 1:200.