Anti-PAAF1 Polyclonal Antibody
Cat: K112318P
Summary:
| 【Product name】：Anti-PAAF1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：80227 | 【Swiss Prot】：Q9BRP4 |
| 【Observed】：46/42kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human PAAF1 | |
| 【Public Immunogen Range】：1-393aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation.
Verified picture:
Western blot analysis with PAAF1 antibody diluted at 1:2000;Lane: HEK-293