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Anti-PAAF1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K112319P - SAlexa Fluor 405
Summary:
【Product name】:Anti-PAAF1 Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:80227 【Swiss Prot】:Q9BRP4
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human PAAF1
【Public Immunogen Range】:1-393aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation.
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