Anti-HMGCL Polyclonal Antibody
Cat: K112330P
Summary:
| 【Product name】：Anti-HMGCL Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3155 | 【Swiss Prot】：P35914 |
| 【Observed】：34kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human HMGCL | |
| 【Public Immunogen Range】：1-326aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with HMGCL antibody diluted at 1:2000;Lane: HepG2,Raji,Liver cancer,Mouse liver,Rat liver.
Immunohistochemistry of paraffin-embedded human thyroid cancer with HMGCL antibody diluted at 1:50.